Amino acids and Anti-Aging

Amino acids as a component of antiaging medicine


Probably the most popular medical topic over the last years has been an issue of possible strategy of stopping or at least slowing the processes of human body ageing and disintegration.

And it is not a surprise that all of us want to become adult, but none of us want to be old or to feel like that.

It is hard to say whether this wish will be fulfilled or not in the near future.

Nevertheless, the knowledge acquired by scientists on the reasons of ageing processes and fight against it are so promising that they become a source of absolutely new branch of preventive medicine – antiaging medicine.

Amino acids can be considered a component of antiaging medicine.

Hormonal changes

If to speak about hormonal changes the most important is a decrease in the level of sex hormones, first of all, estrogens (menopause), testosterone (andropause) and dehydroepiandrosterone (DHEA) or DHEA sulfate (andrenopause).

Besides, there is also a decrease in growth hormone level (somatopause). In recent times special emphasis has been laid on decrease in growth hormone levels as a mean of progression of ageing processes.

Growth hormone (somatotropic hormone, somatotropine, somatotrophic hormone) is synthetized by pituitary body. Its release is regulated by Somatotropin Releasing Factor, STG-RF and somatostatin, synthetized by hypothalamus. This impact is produced partially not by growth hormone, but by Insulin-like growth factor 1, which is released in the liver under the influence of the growth hormone. The most important physiological functions of the growth hormone are participation in cell division process, tissue growth and in increased consumption of amino acids by muscular tissue cells, stimulation of protein synthesis and lipolysis.


Various amino acids are important for the antiaging medicine first of all because they stimulate release of the growth hormone. The amino acid which in practical conditions has maximum effect is glutamine.
So the persons at the age from 32 up to 64 years who have been taking 2 grams of glutamine, in comparison with placebo group, have shown quadruple increase in concentration of growth hormone in the blood plasma. Author of the study has told that dosages less than 1 g presumably will be insufficient, however much higher amounts can also be not effective because they accelerate glutamine cleavage process in the liver

Arginine and lysine

Arginine is also one of amino acids which increase growth hormone release. There was double blind placebo-controlled study in postmenopausal women, so oral daily administration of 9 grams of arginine for 1 month has resulted in ncrease in growth hormone level. One of the studies carried out in Italy, tells that lysine potentiates arginine action. During the period of the study an efficiency of the combined administration of lysine 1200 mg and arginine 1200 mg for male participants of the study at the age from 15 to 20 years old was 10 times higher in comparison with administration of only arginine. One of the studies which participants were healthy elder persons has shown that daily administration of 17 grams of arginine during the period of 14 days provides essential increase in IGF-1. Growth hormone level was not measured in this study.


Glycine plays a significant role in synthesis of connective tissue protein. There is high demand for this amino acid at the anabolic phase. Accordingly its insufficient supply results in higher cleavage of connective tissue protein. Glycine does facilitates recalling of the information from the memory (brain functioning). It does also increase ttention in older persons. Thus its efficiency was marked after only one administration in a small dosage (100 mg only) on an empty stomach. Besides, glycine participates in detox reactions in the liver. In case of administration in a pure form it can stimulate higher release of STH (somatotropic hormone, Somatotropine) by the pituitary body. It happens both at intravenous administration in high dosage – from 250 mg per kg of body weight and at oral administration of about 6 grams of  glycine.



Nutritive substances

per 100 g

Daily portion 6 g


1556.74 kJ
(372.59 kcal)

93.40 kJ
(22.35 kcal)


0.0 g

0.0 g

Carbohydrates 11.48 g 0.68 g


83.33 g

4.99 g


0 g

0 g


50,0 g

3,0 g


13,0 g

0,78 g


12,0 g

0,72 g


11,0 g

0,66 g




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11. Aminosäuren als Bestandteil der Anti-Aging-Medizin
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Quellen: Klaus Arndt und Torsten Albers: Protein und Aminosäuren / Novagenics Verlag Arnsberg / Deutschland
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